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The HYBRIDA Code of Responsible Conduct is part of a broader project that addresses the ethical, legal, and social challenges arising from research using organoids (mini-organs grown in labs). Organoids bring unique ethical questions because they challenge traditional categories: are they more like objects, animals, or human participants? The Code provides guidance for researchers in academia and industry to navigate these uncertainties responsibly. It is built on philosophical, legal, and stakeholder analyses, and includes engagement with the public, vulnerable groups, and regulatory bodies. The document clarifies the moral and ontological status of different types of organoids (e.g. neural, embryo models), identifies gaps in existing regulation and ethics frameworks, and proposes concrete rules and norms to ensure integrity, respect, and transparency in organoid-based research. The Code is intended to complement existing European research integrity regulations (like the ALLEA Code of Conduct), making them more applicable to new biotechnologies.

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