Balancing harms and benefits
ThemesBalancing harms and benefits
What is this about?
Why is this important?
When considering any research project, the potential net benefit should outweigh the potential net harm. This is in line with the universally recognized ethical principles of beneficence (doing good) and non-maleficence (not doing harm). These two principles stem from the belief that human beings have inherent dignity, which was formalized in the UN Declaration of Human Rights (1). In biomedical research, harms will almost inevitably be experienced alongside benefits. That’s why it’s important to carefully assess how important the benefits are and under what cost. These dilemmas should always be communicated to research participants, to ensure fully informed consent.
A number of mid-20th century studies, such as the Tuskegee syphilis experiment, were conducted to examine the natural history of a disease by either deliberately exposing human subjects to damaging stimuli, or by not giving them effective treatment (2). These are some of the most prominent examples of disproportionate harm to benefit.For whom is this important?
The Embassy Editorial team, The Embassy editorial team, Iris Lechner, Stefan Veen, Andrijana Perković Paloš, Ružica Tokalić contributed to this theme. Latest contribution was Mar 25, 2021
