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| | {{Resource | | {{Resource |
| | |Resource Type=Cases | | |Resource Type=Cases |
| − | |Title=The Paolo Macchiarini Case | + | |Title=Artificial tracheas and severe research misconduct |
| − | |Is About=Paolo Macchiarini was considered a pioneer in the field of regenerative medicine using both biological and synthetic scaffolds seeded with patients’ own stem cells as trachea transplants. Macchiarini has been accused of research misconduct and unethically performing experimental surgeries, even on relatively healthy patients. Six of the eight patients who received one of his synthetic trachea transplants have died. Also, accusations have been published that Macchiarini had falsified some of his academic credentials on résumés.
| + | |Is About=This is a factual case.<br /> |
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| − | |Important Because=The Royal Swedisch Academy of Sciences spoke of a ‘crisis of confidence in Swedish medical research’ after the Karolinska Institute, where Macchiarini worked, first stated that Macchiarini was found guilty of research fraud, but was found not guilty by the second inquiry. As a result of the case, several measures have been planned by [https://ki.se/en/about/action-plan-following-the-investigations-of-the-macchiarini-case Karolinska Institute]. The measures include teaching research integrity to junior scientists, new procedures in cases of suspected scientific misconduct and a compulsary log book for research documentation<ref>https://www.nrin.nl/ri-collection/library/case-histories/macchiarini-case/<br /></ref> . | |
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| | |Important For=researchers; research leaders; All stakeholders in research | | |Important For=researchers; research leaders; All stakeholders in research |
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| | |Has Location=Sweden | | |Has Location=Sweden |
| | |Has Virtue And Value=Honesty; Respect; Reliability | | |Has Virtue And Value=Honesty; Respect; Reliability |
| − | |Has Good Practice And Misconduct=Balancing harms and benefits; Fabrication; Falsification; Research with Humans; Research with Animals; Lack of Ethical Review; Safety; Fraud; Negligence; Death; Ethics; Research Misconduct | + | |Has Good Practice And Misconduct=Fabrication; Falsification; Research with Humans; Research with Animals; Lack of Ethical Review; Safety; Fraud; Negligence; Ethics; Research Misconduct |
| | |Related To Research Area=Medical and Health Sciences | | |Related To Research Area=Medical and Health Sciences |
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