Resource:A562c502-9648-4b90-b823-125bbb53e2b6

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Cases

Lapses in Oversight Compromise Omics Results

What is this about?

Commentary on the Anil Potti case discussing relevant institutional changes in avoiding such misconduct. Potti was a researcher of cancer genomics at Duke University in Durham, North Carolina. His studies had linked changes in the expression of patients' genes with how they responded to cancer treatments, and independent statisticians had raised concerns about published papers linked to the work before clinical trials were initiated based on them. As the commentary highlights, there were a list of failures in the system of research oversight and integrity at the research institution, which must be corrected.

Why is this important?

It highlights the importance of institutional practices on research oversight and integrity that could serve as safeguards against research misconduct and other ethics failures.

For whom is this important?

ResearchersAdministratorsEthics committee membersPolicy makers

Other information

When

• 2006

Where

• United Kingdom
• Duke University

Virtues & Values

• Honesty

Good Practices & Misconduct

• Falsification
• Clinical trials
• Retraction
• Conflict of Interest
• Research Environments
• Research Misconduct

Research Area

• Clinical Medicine
• LS 02 - Genetics, Genomics, Bioinformatics and Systems Biology