Guest authorship, mortality reporting, and integrity in rofecoxib studies
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Guest authorship, mortality reporting, and integrity in rofecoxib studies
What is this about?
The study by Drs Psaty and Kronmal and the accompanying Editorial by Drs DeAngelis and Fontanarosa regarding rofecoxib illustrate the recurring problem of discretionary or data-driven analysis[1].
Why is this important?
Given the possibility of selective analysis based on observed data and the risk of positive results due to chance alone, it is critical to know in detail which analyses were prespecified and when the prespecification occurred[2].
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