Clinical Trials and Drug Promotion: Selective Reporting of Study 329
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Clinical Trials and Drug Promotion: Selective Reporting of Study 329
What is this about?
This article describes the ethical issues regarding the Study 329. The Study wanted to determine the efficacy and safety of imipramine and paroxetine in the treatment of adolescents with major depression. However, it did not comply with the study protocol and ignored important safety problems, which led to some harmful effects.