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Revision as of 15:28, 24 August 2020

Cases

Guest Authorship, Mortality Reporting, and Integrity in Rofecoxib Studies

What is this about?

The study by Drs X and Y and the accompanying Editorial by Drs Z and Q regarding rofecoxib illustrate the recurring problem of discretionary or data-driven analysis[1] This is a facutal case.

  1. FitzGerald, Garret A. "Guest authorship, mortality reporting, and integrity in rofecoxib studies." JAMA 300.8 (2008): 900-906.

Why is this important?

Given the possibility of selective analysis based on observed data and the risk of positive results due to chance alone, it is critical to know in detail which analyses were prespecified and when the prespecification occurred[1].

  1. FitzGerald, Garret A. "Guest authorship, mortality reporting, and integrity in rofecoxib studies." JAMA 300.8 (2008): 900-906.

For whom is this important?

Other information

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